Development and evaluation of sustained release losartan potassium matrix tablet using kollidon SR as release retardant
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چکیده
منابع مشابه
Development and Evaluation of Sustained Release Matrix Tablet of Lamivudine
The study was obtained to develop oral controlled release matrix tablets of Lamivudine having different proportion of Guar gum (retardant polymer) and to study the effect of formulation factor such as polymer proportion on the invitro release. The prepared granules were evaluated such as angle of repose, loose bulk density, tapped bulk density and compressibility index and satisfactory results ...
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In the present investigation, an attempt has been made to increase therapeutic efficacy, reduce frequency of administration and improve patient compliance by developing sustained release matrix tablets of theophylline. Sustained release matrix tablets of theophylline were developed by using drug and different concentrations of polymer such as 10, 20, 30, 40 and 50%. Hydroxypropylmethylcellulose...
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The objective of research was to explore the suitability of lipids like compritol 888 ATO and stearic acid as release retardant to develop sustained release (SR) tablets. The SR micromatrices of lipid (s) and glipizide were prepared (LM1- LM6) as intermediate product by fusion method and assessed for various pharmacotechnical properties. Micromatrices were formulated as SR tablets (F1-F6) by di...
متن کاملFormulation and Evaluation of Sustained Release Matrix Tablets of Glipizide
The purpose of this study was to develop a new monolithic matrix tablet to completely deliver glipizide in a zero order manner over a sustained period. Two approaches were examined using drug in a formulation that contain polymer like hydroxylpropyl methyl-cellulose K 100 (HPMCK) and Eudragit L 100. The granules were prepared by wet granulation method and thereby formulated as F-1, F-2. F...
متن کاملIn vitro Release Kinetics Study of Diltiazem Hydrochloride from Wax and Kollidon SR Based Matrix Tablets
Extended-release matrix tablets of diltiazem hydrochloride (DTZ) were prepared using waxy materials alone or in combination with Kollidon SR. Matrix waxy materials were carnauba wax (CW), bees wax (BW), cetyl alcohol (CA) and glyceryl monostearate (GMS). Dissolution studies were carried out by using a six stations USP XXII type 1 apparatus. The in vitro drug release study was done in 1000 ml ph...
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ژورنال
عنوان ژورنال: Brazilian Journal of Pharmaceutical Sciences
سال: 2012
ISSN: 1984-8250
DOI: 10.1590/s1984-82502012000400005